The 2013 paper at the link below was submitted for publication by the Journal of Law, Medicine & Ethics. It paints a gloomy picture of increasing corruption in the pharmaceutical industry, and the authors offer suggestions that would serve to reverse this trend of drugs that are both more dangerous and less efficacious.
https://pubmed.ncbi.nlm.nih.gov/24088149/
Separating the funding of clinical trials from their conduct, analysis, and publication.
Independent FDA leadership.
Full public funding for all FDA activities.
Measures to discourage R&D on drugs with few, if any, new clinical benefits.
The creation of a National Drug Safety Board.
Quotes from the paper's abstract:
Over the past 35 years, patients have suffered from a largely hidden epidemic of side effects from drugs that usually have few offsetting benefits.
The pharmaceutical industry has corrupted the practice of medicine through its influence over what drugs are developed, how they are tested, and how medical knowledge is created.
Since 1906, heavy commercial influence has compromised congressional legislation to protect the public from unsafe drugs.
The authorization of user fees in 1992 has turned drug companies into the FDA's prime clients, deepening the regulatory and cultural capture of the agency.
Industry has demanded shorter average review times and, with less time to thoroughly review evidence, increased hospitalizations and deaths have resulted.
Meeting the needs of the drug companies has taken priority over meeting the needs of patients.
Unless this corruption of regulatory intent is reversed, the situation will continue to deteriorate.
Now, in the present, obviously these suggestions were not taken, and we have arrived, again obviously, at a paroxysmal example of the problems these authors are gravely concerned with, namely the mRNA injections that were mandated, and the ensuing public hysteria pro and con resulting from that mandate.
And it seems the intransigence of the pharmaceutical industry, with its supportive legislative bodies; and the World Health Organization, a non-elected intergovernmental organization that now seeks to mandate drugs to the entire population of the world, is increasingly more rooted than ever.
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The First Turning: A High
A High occurs after a period of great turmoil is resolved. During a High, a new social order is put in place. Government is strong and active, and public services are expanded. Values like individualism fall out of fashion and are replaced by more collective values. Income inequality and unemployment fall, and productivity increases. Class inequality also falls, but gender gaps increase. Children are given greater autonomy.
The Second Turning: An Awakening
An Awakening occurs when people pull away from the social order imposed during the High, resulting in a cultural revolution. People question and defy the institutions and regulations established during the High as the need for them falls out of living memory.
People also reject collective values and the ideals of duty and conformity in favor of individual rights. Government weakens, and free markets begin to overshadow public services. Violence and crime increase, as do income inequality and class divisions. Gender divisions become less strict, and child-rearing becomes more lenient.
The Third Turning: An Unraveling
An Unraveling occurs when society embraces the new order put in place during the Awakening. Trust in government and establishments continues to decline, and people become more passionate about and extreme in their beliefs. Communities become divided over morals, and unified action becomes more difficult.
People become tribal or nationalistic and suspicious of anything that doesn’t fit their values. Individualism is at its highest, and free markets become even more favored. Violence, crime, and income inequality reach their peak. Gender divisions are even less strict, and society becomes more protective of children.
The Fourth Turning: A Crisis
A Crisis occurs when a catalyst ignites a significant change in society. The anxious, pessimistic, and pre-cataclysmic mood of the Unraveling primes people to respond in a way that creates a societal upheaval.
In response to the panic, people begin to unite as communities to establish a new social order that demands collective sacrifice to resolve the nation’s problems. The government is appointed to implement and enforce this social order.
Violence, crime, and income inequality decrease. Gender divisions increase again. Protectiveness over children is at its highest.
The risk of national violence such as revolution, civil war, and foreign war increases. Leaders characterize foreign and political opponents as immoral and refuse to compromise, and the use of highly destructive weapons increases for the sake of decisive victories.
As a result of the Crisis, society is unrecognizably transformed. The resolution of the Crisis cements the new social order and results in an end to wars.
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