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https://medicalxpress.com/news/2019-05-zombie-cells-buildup-body-role.html
But why wait for science to figure out how nature works?
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fast your way to autophagy
Autophagy is a "body intelligence" process. Science doesn't understand how this works yet, only that it does. How is it intelligent? It's a normal autonomic function that goes after pathogenic tissues, along with stored fats for energy. Extended autophagy (we get a little of it when we sleep) is induced with calorie restriction. This is why the majority of people come out of a "regenerative" water only fast looking 10 years younger and feeling better than they have in ages. And "therapeutic" water fasting, which should only be undertaken under expert supervision in an established fasting clinic like True North Health Center in Santa Rosa California, is more effective for healing the majority of "lifestyle" diseases than any other modality.
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https://www.healthpromoting.com/
The energy for functioning and continuation of human life can only come from the three "macronutrients", carbohydrates, fats, and proteins. If carbohydrates are available (glycogen stored in muscles and liver) the body will use those first. If carb stores become depleted the body shifts to burning fat stores (spread throughout the body). If fat stores become depleted the body shifts to burning proteins for energy.
There is a time limit to "rapid and continuous" autophagy (water fasting) based on levels of stored fat that can be used for energy. After fat stores are depleted the body shifts from "fasting" (burning fat for energy) to "starvation", and begins consuming least critical proteins. We know "least critical" proteins are consumed because autopsies of starvation victims have shown the critical organs to have been "spared". (This is why concentration camp victims can recover completely.) The energy in starvation comes mostly from muscle tissue proteins converted to energy.
Expert supervision of therapeutic water fasting is necessary to ensure the fast is terminated well before the shift to proteins as fuel, but long enough to achieve maximum benefit. Each patient must be assessed individually before the fast and every day throughout the fast. Co-factors are assessed, such as age and types and degrees of ongoing disease processes.
Expert supervision of therapeutic water fasting is necessary to ensure the fast is terminated well before the shift to proteins as fuel, but long enough to achieve maximum benefit. Each patient must be assessed individually before the fast and every day throughout the fast. Co-factors are assessed, such as age and types and degrees of ongoing disease processes.
True North Health Center has an unblemished record for safety after supervising many thousands of fasts over decades. Compare that to any hospital:
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An interesting thought experiment: what if there were as many fasting clinics as there are hospitals, and fasting was widely recognized as the safe and effective treatment that it is? Hospitals could well lose about 2/3's of their business over time, destroying the business model of the overall healthcare industry in the process. Buuut...water fasting isn't really all that profitable compared to what we have now, the most expensive and least effective health care system (on a developed world basis).
You don't need to wait for science to catch up by developing a pill ! (It ain't ever going to be as effective anyway). Intermittent fasting does not require supervision (in most cases) once you learn the options and how to proceed, and autophagy is increased to some significant degree whichever method you choose. There are (probably) hundreds of websites explaining intermittent fasting, this one is pretty comprehensive:
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Intermittent Fasting 101 — The Ultimate Beginner's Guide
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Intermittent Fasting 101 — The Ultimate Beginner's Guide